HealthPROMISE demonstrated a significant improvement in patients' quality of care. In a pragmatic randomized trial at Mount Sinai Medical Center (MSMC), baseline e- PROs were measured using online questionnaires delivered through the app that assessed health literacy, disease severity, general health status, and demographic information. Patients using HealthPROMISE could update their e-PRO information and receive a disease summary. Patients could also communicate over the HealthPROMISE app and discuss results with providers.

At baseline, patients in the intervention arm reported a mean quality of life score of 30.3 ± 11.3. The last available follow-up QoL scores showed improvement among patients using HealthPROMISE to 25.3 ± 11.3 (p < 0.001). Patients engaging with HealthPROMISE reported more equitable participation in their care decision-making process, and showed improved health outcomes compared to patients not using HealthPROMISE.