1. Pneumonia is by far the most common significant presentation of COVID-19 infection, typically characterized by fever, cough, dyspnea and bilateral lung infiltrates on chest imaging. Most infections are not extreme, while many patients suffering from a serious infection.
  2. In a report from the Chinese Center for Disease Control and Prevention which included approximately 44,500 confirmed infections with disease severity projections-
    • 5 percent were critical (e.g., Shock, respiratory failure and multi-organ failure).
    • 14 percent were serious (e.g. dyspnea, hypoxia)
    • 81 percent were moderate (no or mild pneumonia)
  3. According to WHO, the case-fatality rate in Wuhan ranged from 2 to 4 percent and in the rest of China was 0.7 percent. Most of the fatal cases occurred in patients of older age or underlying health conditions.
  4. Gastrointestinal symptoms like nausea and diarrhea have been reported in some cases.
  5. Although lymphopenia appears to be the most common sign leukopenia and leukocytosis are also been reported.
  6. Elevated aminotransferase levels
  7. Elevated procalcitonin levels are documented in patients requiring intensive care unit care.
  8. Based on a study of 138 confirmed COVID- 19 pneumonia patients in Wuhan 
    • 99 percent reported having fever 
    • 59 percent had a dry cough
    • 35 percent had myalgias
    • 31 percent developed dyspnea, over a period of 5 days of the disease.
    • Lymphopenia was common among the cases
    • CT of the chest showed bilateral patchy abnormalities or ground-glass opacities.
    • 20 percent has developed acute respiratory distress syndrome( ARDS) 
    • 12.3 percent required mechanical ventilation 
    • 6 patients have died- their lab reports showed severe lymphopenia and high D-dimer levels. 


References- 

  1. https://jamanetwork.com/journals/jama/fullarticle/2762130
  2. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html
  3. https://www.ncbi.nlm.nih.gov/pubmed?term=32007143
  4. https://pubmed.ncbi.nlm.nih.gov/32031570-clinical-characteristics-of-138-hospitalized-patients-with-2019-novel-coronavirus-infected-pneumonia-in-wuhan-china/?from_single_result=32031570