- Pneumonia is by far the most common significant presentation of COVID-19 infection, typically characterized by fever, cough, dyspnea and bilateral lung infiltrates on chest imaging. Most infections are not extreme, while many patients suffering from a serious infection.
- In a report from the Chinese Center for Disease Control and Prevention which included approximately 44,500 confirmed infections with disease severity projections-
- 5 percent were critical (e.g., Shock, respiratory failure and multi-organ failure).
- 14 percent were serious (e.g. dyspnea, hypoxia)
- 81 percent were moderate (no or mild pneumonia)
- According to WHO, the case-fatality rate in Wuhan ranged from 2 to 4 percent and in the rest of China was 0.7 percent. Most of the fatal cases occurred in patients of older age or underlying health conditions.
- Gastrointestinal symptoms like nausea and diarrhea have been reported in some cases.
- Although lymphopenia appears to be the most common sign leukopenia and leukocytosis are also been reported.
- Elevated aminotransferase levels
- Elevated procalcitonin levels are documented in patients requiring intensive care unit care.
- Based on a study of 138 confirmed COVID- 19 pneumonia patients in Wuhan
- 99 percent reported having fever
- 59 percent had a dry cough
- 35 percent had myalgias
- 31 percent developed dyspnea, over a period of 5 days of the disease.
- Lymphopenia was common among the cases
- CT of the chest showed bilateral patchy abnormalities or ground-glass opacities.
- 20 percent has developed acute respiratory distress syndrome( ARDS)
- 12.3 percent required mechanical ventilation
- 6 patients have died- their lab reports showed severe lymphopenia and high D-dimer levels.
References-
- https://jamanetwork.com/journals/jama/fullarticle/2762130
- https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html
- https://www.ncbi.nlm.nih.gov/pubmed?term=32007143
- https://pubmed.ncbi.nlm.nih.gov/32031570-clinical-characteristics-of-138-hospitalized-patients-with-2019-novel-coronavirus-infected-pneumonia-in-wuhan-china/?from_single_result=32031570